mIRage, Submicron IR spectroscopy

mIRage

Submicron IR spectroscopy

 

microscopy IR

 



microscopy IR


microscopy IR

The mIRage™ IR microscope is an innovative new system uniquely providing submicron IR spectroscopy and imaging across a wide variety of applications.
Using a proprietary Anasys technique based upon photothermal IR spectroscopy, mIRage breaks the diffraction limit and bridges the gap between conventional IR microspectroscopy and nanoscale IR spectroscopy.

The Mirage IR microscope changes the field of IR spectroscopy with a novel approach to achieving sub-micron resolution IR.

 

  • Submicron IR spectroscopy and imaging
  • Transmission quality IR spectra in reflection mode
  • IR wavelength independent spatial resolution
  • Fast, easy to use, optical non contact technique

 

 


Eliminates need for thin sections,
transmission FTIR quality spectra in reflection mode


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For the first time, Mirage provides IR wavelength independent spatial resolution, highly sensitive IR measurements and transmission quality absorption spectra in reflection mode. Thus dramatically simplifying sample preparation, eliminating the need for thin samples, enabling measurement of thicker samples and improving measurement turnaround times.

microscopy IR

 

  • No need for thin

Bone sample: Reflection mode IR Spectra and hyperspectral imaging 25-µm x 25-µm array, 500-nm spacing. Left: Single wavelength image (1058 cm-1) from Hyperspectral data set Right: Single-pixel spectrum – 1s collection time

 

microscopy IR

 

  • Resolve submicron features

Packaging sample section: Reflection spectra-line array across multiple regions. 138 spectra, 0.5 µm spectrum spacing, 10 co-averages/spectra. 12 sec/spectra collection time.

 

 

 

 

microscopy IR

 

  • IR spectroscopy from macroscale to microscale and down to nanoscale

he Mirage IR microscope can also combine with the nanoIR™ platform to enable microIR to nanoIR capability, measuring sample features from submicron resolution to below 10nm

 

 

 

 

microscopy IR

 

  • Fast, easy to use, optical contact technique

The Mirage system overcomes the IR diffraction limit with an innovative technique utilizing the same fundamental principles that govern photothermal based AFM-IR.

A tunable pulsed mid-IR laser induces photothermal effects into a sample surface, which are measured using a visible probe laser focused on the sample.

The measurements are collected in a fast, easy to use manner without the need for contact-based techniques like ATR spectroscopy

 

 

 

  • mIRage covers a broad applications range

Mirage provides unique, first and only data covering a wide range of applications including polymeric samples and materials, life science (bone, cells, hair), complex pharmaceutical samples and organic defects and contaminants in micro-electronics as well as many more.

 

Polymers life science pharmaceuticals
microscopy IR microscopy IR microscopy IR

Multilayer film sample: Reflection mode spectral line array on each layer within cross sectioned film sample. 100 scans/spectrum (140 sec). Inset: mIRage optical image of sample cross section, embedded in epoxy stub.

Porcine stem cell sample: Reflection mode single wavelength image (1540 cm-1) extracted from hyperspectral data set. 30 x 30 µm image with 500 nm point spacing, 1 spectrum/point (1s).

Drug/Polymer blend sample: Refletion mode single wavelength image (50 x 50 µm) collected at 1666 cm-1, highlighting distribution of the drug, dexamethasone, in a PLGA polymer matrix.

 


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